What does set off mean? Marketing Team Updated July 19, 2018 23:32 Follow Set off is when colour from your print job is transferred to another part of the job, leaving ink marks. Related articles What is a PDF? How do I supply artwork for a multiple sets order? What does "sets" mean? How do I submit artwork for a 4pp leaflet? What does self-cover mean? Comments 0 comments Article is closed for comments.